The pioneering p300/CBP drug development company
Inobrodib; oral first-in-class p300/CBP small molecule inhibitor drug to treat cancer
Inobrodib; oral first-in-class p300/CBP inhibitor drug
CellCentric is a clinical stage biotech company; science driven, patient focused. We lead in the inhibition of p300/CBP to treat specific cancers, notably multiple myeloma. Our aim is to develop our first-in-class drug, inobrodib, as quickly and as effectively as possible for the benefit of patients.
About inobrodib
Inobrodib is a small molecule which disrupts the growth of cancer cells by inhibiting twin gene co-activation factors, p300 and CBP. It binds to the bromodomain of the twin proteins. It is highly selective and does not impact similar pockets on other proteins. Inobrodib displaces p300/CBP from specific parts of chromatin, reducing the activation of genes involved in tumour progression, including IRF4 and MYC. The drug continues to be tested in clinical trials, where it is showing promise particularly in treating patients with multiple myeloma.
Patient preference
Many new cancer treatments are complex and require significant hospitalisation time to administer or have side effects that can be challenging and costly to address. Inobrodib is an oral drug that can be taken at home. This is a key patient preference, allowing people to feel more in control, and less burden on their families. Tolerated and easier to administer drugs also help address health inequities, ensuring greater uptake by the widest communities.
Latest tweets from @CellCentric
We’ll be at ASH24, sharing latest Phase II clinical data on our oral small molecule p300/CBP inhibitor, inobrodib. See: https://www.cellcentric.com/press-release/cellcentric-to-share-latest-inobrodib-phase-ii-data-oral-presentation-at-ash-2024/
We’ll be at #ASH24. Presentation on our novel MoA oral drug, to treat multiple myeloma. See: https://www.cellcentric.com/press-release/cellcentric-to-share-latest-inobrodib-phase-ii-data-oral-presentation-at-ash-2024/ Many thanks @DrEmmaSearle, The Christie NHS Fdn Trust.
We are delighted to collaborate with the American Cancer Society CAN, gaining insights on needs and preferences of people with multiple myeloma. @ACSCAN
We’ll be at ASH24, sharing latest Phase II clinical data on our oral small molecule p300/CBP inhibitor, inobrodib. See: https://www.cellcentric.com/press-release/cellcentric-to-share-latest-inobrodib-phase-ii-data-oral-presentation-at-ash-2024/
We’ll be at #ASH24. Presentation on our novel MoA oral drug, to treat multiple myeloma. See: https://www.cellcentric.com/press-release/cellcentric-to-share-latest-inobrodib-phase-ii-data-oral-presentation-at-ash-2024/ Many thanks @DrEmmaSearle, The Christie NHS Fdn Trust.
We are delighted to collaborate with the American Cancer Society CAN, gaining insights on needs and preferences of people with multiple myeloma. @ACSCAN
We’ll be at ASH24, sharing latest Phase II clinical data on our oral small molecule p300/CBP inhibitor, inobrodib. See: https://www.cellcentric.com/press-release/cellcentric-to-share-latest-inobrodib-phase-ii-data-oral-presentation-at-ash-2024/
We’ll be at #ASH24. Presentation on our novel MoA oral drug, to treat multiple myeloma. See: https://www.cellcentric.com/press-release/cellcentric-to-share-latest-inobrodib-phase-ii-data-oral-presentation-at-ash-2024/ Many thanks @DrEmmaSearle, The Christie NHS Fdn Trust.
We are delighted to collaborate with the American Cancer Society CAN, gaining insights on needs and preferences of people with multiple myeloma. @ACSCAN