The pioneering p300/CBP drug development company
Transforming outcomes and quality of life for people with cancer
Inobrodib; oral first-in-class p300/CBP inhibitor drug
CellCentric is a clinical stage biotech company; science driven, patient focused. We lead in the inhibition of p300/CBP to treat multiple specific cancer types. Our aim is to develop our first-in-class drug, inobrodib, as quickly and as effectively as possible for the benefit of patients.
About inobrodib
Inobrodib is a small molecule which disrupts the growth of cancer cells by inhibiting twin gene activation factors, p300 and CBP, involved in tumour progression. It binds to a specific part of the twin proteins (the bromodomain). It is highly selective and does not impact similar pockets on other proteins. Through this action inobrodib reduces the expression of key cancer drivers; including IRF4, MYC and the androgen receptor (AR and its variants).
Inobrodib is a first in class drug which has shown efficacy in treating multiple specific cancer types, with the most advanced data in relapsed refractory multiple myeloma.
Latest tweets from @CellCentric
Great news. CellCentric secures further investment from BrightEdge, the American Cancer Society’s impact investment and innovation arm. See: https://www.cellcentric.com/press-release/cellcentric-secures-further-investment-from-brightedge/
Looking forward to IMS, end Sept. Inobrodib continuing to progress in clinical trials, treating R/R multiple myeloma and other haem malignancies. https://www.myelomasociety.org/events/20th-ims-annual-meeting/
Great to feature in @AmericanCancer, BrightEdge’s annual rpt: https://lnkd.in/eHimR4DR Aligned missions: addressing healthcare burden & inequity. Inobrodib, novel oral oncology drug, at home admin.
Great news. CellCentric secures further investment from BrightEdge, the American Cancer Society’s impact investment and innovation arm. See: https://www.cellcentric.com/press-release/cellcentric-secures-further-investment-from-brightedge/
Looking forward to IMS, end Sept. Inobrodib continuing to progress in clinical trials, treating R/R multiple myeloma and other haem malignancies. https://www.myelomasociety.org/events/20th-ims-annual-meeting/
Great to feature in @AmericanCancer, BrightEdge’s annual rpt: https://lnkd.in/eHimR4DR Aligned missions: addressing healthcare burden & inequity. Inobrodib, novel oral oncology drug, at home admin.
Great news. CellCentric secures further investment from BrightEdge, the American Cancer Society’s impact investment and innovation arm. See: https://www.cellcentric.com/press-release/cellcentric-secures-further-investment-from-brightedge/
Looking forward to IMS, end Sept. Inobrodib continuing to progress in clinical trials, treating R/R multiple myeloma and other haem malignancies. https://www.myelomasociety.org/events/20th-ims-annual-meeting/
Great to feature in @AmericanCancer, BrightEdge’s annual rpt: https://lnkd.in/eHimR4DR Aligned missions: addressing healthcare burden & inequity. Inobrodib, novel oral oncology drug, at home admin.