CellCentric presents further CCS1477 pre-clinical efficacy data at AACR.April 3rd 2017:CellCentric’s cancer drug candidate CCS1477 is initially targeted for the treatment of castrate resistant prostate cancer (CRPC). Further supporting data is presented today at the 2017 annual meeting of the American Association for Cancer Research (AACR) in Washington, DC. CCS1477 can also be used against tumours that harbour p300 or CBP mutations, opening up application areas including bladder, lung and haematological cancers.
CellCentric’s novel p300/CBP inhibitor, CCS1477 advancing to the clinic.February 16th 2017:CellCentric has developed a potent, selective, orally bioavailable small molecule inhibitor of p300/CBP. These targets are key regulators of cancer cells, and specifically play a critical role in the progression of the aggressive form of prostate cancer. Key pre-clinical efficacy data on CellCentric’s compound CCS1477 is presented today at GU-ASCO, Orlando (1).