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Cancer Cell…Nicosia, Searle, Somervaille (2023)

Therapeutic targeting of EP300/CBP by bromodomain inhibition in hematologic malignancies

Applications

Inobrodib is currently being evaluated for safety and efficacy in different multiple myeloma patient populations

Multiple Myeloma

Multiple myeloma (MM) and other hematological malignancies are regulated in part by p300/CBP.

Other Potential Applications

Inobrodib may have therapeutic utility in other p300/CBP-regulated cancers including acute myeloid leukemia (AML), lymphomas, solid tumors and targeted tumors with specific genetic mutations.

About CellCentric

CellCentric is a clinical-stage biopharmaceutical company focused on the development of a first-in-class oral p300/CBP inhibitor to treat multiple myeloma and other cancer types.

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