Claire Sadler

Toxicology Consultant. ApconiX. Previously UK Discovery Safety Director, AstraZeneca

Claire is an experienced project toxicologist working with the consultancy ApconiX Ltd. Previously she was Director of UK Discovery Safety within AstraZeneca. Claire is proficient at designing and implementing bespoke safety packages, incorporating in vitro and in vivo experiments, that address safety issues, with the aim to provide prospective understanding of the major safety risks, thereby influencing chemical design, creating mitigation strategies and expediting progression through GLP-safety studies and initiation of clinical trials. Claire has worked primarily in the Oncology and Infection therapeutic areas, with direct involvement in multiple compounds progressing into clinical trials.